Toxin-Antitoxin systems: their role in persistence, biofilm formation, and pathogenicity
نویسندگان
چکیده
منابع مشابه
association between toxin-antitoxin systems and biofilm formation
conclusions the analysis recommended that ta genes are prevalent in clinical isolates of e. coli strains. the analysis revealed that hipba ta system is associated with biofilm formation. results the results of the analysis revealed that 107 e. coli isolates were potent for biofilm formation by cra. the findings by microtiter plates showed that 102 e. coli isolates were biofilm producers. the re...
متن کاملAssociation Between Toxin-Antitoxin Systems and Biofilm Formation
BACKGROUND Toxin-antitoxin (TA) systems are found on the chromosomes and plasmids of many Bacteria such as Escherichia coli. The roles of TA systems in bacteria are enigmatic. Multiple biological functions of TA systems are proposed including growth modulation, persistence, and biofilm formation. Biofilms of E. coli are cause of urinary tract infections, as well as bacteraemia. OBJECTIVES The ...
متن کاملMolecular Detection of Type II Toxin-Antitoxin Systems and their Association with Antibiotic Resistance and Biofilm Formation in Clinical Acinetobacter baumannii Isolates of Burn Patients
Background and purpose: Burn wounds are a good host for infections. Acinetobacter baumannii is an opportunistic bacterium in patients with burn infections. Toxin-antitoxin systems (TAS) are genetic elements that are essential for antibiotic resistance and biofilm formation in bacteria, including higBA and relBE TA systems. The present study aimed to investigate the frequency of higBA and relBE...
متن کاملMqsR/MqsA Toxin/Antitoxin System Regulates Persistence and Biofilm Formation in Pseudomonas putida KT2440
Bacterial toxin/antitoxin (TA) systems have received increasing attention due to their prevalence, diverse structures, and important physiological functions. In this study, we identified and characterized a type II TA system in a soil bacterium Pseudomonas putida KT2440. This TA system belongs to the MqsR/MqsA family. We found that PP_4205 (MqsR) greatly inhibits cell growth in P. putida KT2440...
متن کاملToxin-antitoxin systems in Escherichia coli influence biofilm formation through YjgK (TabA) and fimbriae.
The roles of toxin-antitoxin (TA) systems in bacteria have been debated. Here, the role of five TA systems in regard to biofilm development was investigated (listed as toxin/antitoxin: MazF/MazE, RelE/RelB, ChpB, YoeB/YefM, and YafQ/DinJ). Although these multiple TA systems were reported previously to not impact bacterial fitness, we found that deletion of the five TA systems decreased biofilm ...
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ژورنال
عنوان ژورنال: Pathogens and Disease
سال: 2014
ISSN: 2049-632X
DOI: 10.1111/2049-632x.12145